STUDIES ON ANTIMICROBIAL SUBSTANCE B 44 P (STREPTOVARICIN) PRODUCED BY A STRAIN OF ACTINOMYCETES. I

Structural studies on ebelactone A and B, esterase inhibitors produced by actinomycetes.

In the course of our studies on enzyme inhibitors produced by microorganisms, two potent esterase inhibitors named ebelactone A and B, were isolated from the cultured broth of the strain MG7-G1 which was closely related to Streptomyces aburaviensis1). They were determined to be new members of mycolic acid /3-lactone. As reported in our previous papers2.3), esterastin, an esterase inhibitor prod...

Characteristics of a bacteriocin -like substance produced by Clostridium haemolyticum strain IRP - 135

Antimicrobial potential of Actinomycetes by NRPS and PKS-I pathways

Background Actinomycetes may account for 10 to 30% of the total soil rhizosphere microorganisms. The attention given to the actinomycetes in biotechnological applications is a result of their metabolic versatility that is accompanied by the production of primary and secondary metabolites of economic importance, which are a promising source of products (e.g., antibiotics, enzyme inhibitors, anti...

characteristics of a bacteriocin -like substance produced by clostridium haemolyticum strain irp - 135

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Studies on the thermophilic actinomycetes. I. Methods of cultivation.

A total of 1,000 isolates of thermophilic actinomycetes representing two genera, Streptomyces and Thermoactinomyces, were studied. Media for cultivation and for physiological studies were designed. Differences between the two genera are noted and taxonomic criteria for the genus Thermoactinomyces are suggested. The importance of the nutritional environment to the thermophilic habit is noted.